High diluted molecules and gene expression

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منابع مشابه

High diluted molecules and gene expression

Two recently published papers reported that water/ethanol dilutions of Gelsemium sempervirens Ait. extracts could modify gene expression on in vitro human neuronal cells (Marzotto et al., 2014; Olioso et al., 2014). Both papers were performed with the purpose to demonstrate cellular activity of G. sempervirens dilutions, on suited standardized cultures, and confirm the behavioral evidence previ...

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Gene expression and highly diluted molecules

Plants of the genus Gelsemium have measurable effects on anxiety-like symptoms in laboratory models (Magnani et al., 2010; Liu et al., 2013; Meyer et al., 2013; Jin et al., 2014). Searching for a possible mechanism of action, we found that very low doses and homeopathic dilutions of Gelsemium sempervirens (Gelsemium) modulate the expression of genes involved in neuronal functions (G-protein cou...

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Hormetic effects of extremely diluted solutions on gene expression.

This paper summarizes the results of investigations showing how molecular biological tools, such as DNA-microarrays, can provide useful suggestions about the behaviour of human organisms treated with microamounts of drugs or homeopathic medicines. The results reviewed here suggest firstly that the action of drugs is not quenched by ultra-high dilution and proceeds through modulation of gene exp...

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Simulated Microgravity Condition Alters the Gene Expression of some ECM and Adhesive Molecules in Adipose-Derived Stem Cells

Adipose-derived stem cells (ADSCs) are widely used for tissue engineering and regenerative medicine. The beneficial effects of ADSCs on wound healing have already been reported. Remodeling of extracellular matrix (ECM) is the most important physiological event during the wound healing. ECM is sensitive to mechanical stresses and the expression of its components can be therefore influenced. The ...

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Cloning and high level expression of bovine interferon gamma gene in eukaryotic cells (COS-7)

Interferon gamma (IFN-γ) is one of the key cytokines in defining T helper 1 lymphocyte immuneresponses. In this study, the bovine IFN-γ gene was cloned from spleen tissue RNA using the reversetranscription-polymerase chain reaction (RT-PCR). IFN-γ cDNA was sub-cloned and expressed inmammalian expression plasmid (pcDNA3.1(+)) under the control of the human cytomegalovirus (CMV)promoter. The pred...

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ژورنال

عنوان ژورنال: Frontiers in Pharmacology

سال: 2014

ISSN: 1663-9812

DOI: 10.3389/fphar.2014.00183